Prescription Poker

Prescription Poker: Playing the Odds with Medications unpacks this question through a detailed analysis of commonly prescribed heart (and other) medications and their often-low success rates.

Through a deep dive into pharmaceutical-sponsored trials, R. L. Aplin, MD, demonstrates how numerous patients will receive little to no benefit for every one patient who reaps the medication’s intended result. This number needed to treat, or NNT, is the “absolute” reduction in risk—and a well-kept secret thanks in part to big pharma’s influence in health care. Prescription Poker reveals the likelihood of medication success and brings to life the way doctors and other providers are influenced to write the next “lifesaving” prescription. With that in mind, this book is a consumer-advocate must-read for patients and their families, many of whom struggle to afford their medications, and for those who wonder if the side effects of the drugs they’re on are worth enduring. 

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Frequently Asked Questions

Frequently Asked Questions

Who should read this book?

Why Prescription Poker?

What are the similarities between poker and prescription medications?

What is the Number Needed To Treat (NNT)?

“It is a scientific fact that your body will not absorb cholesterol if you take it from another person’s plate.”

—Dave Barry

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© 2025 Richard Aplin, MD. All rights reserved.

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© 2025 Richard Aplin, MD. All rights reserved.

Disclaimer

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© 2025 Richard Aplin, MD. All rights reserved.

Disclaimer

LISTEN